MicroRNAs: Target Recognition and Regulatory Functions
Name
Bartel-2009-MicroRNAs_ Target Re.pdf
Size
2.36 MB
Format
Adobe PDF
Checksum (MD5)
e33196687af9c44c583f64bc1e9b2ae8
Author(s)
Bartel, David
Date Issued
January 2009
Journal
Cell
Publisher
Elsevier B.V.
Citation
Bartel, David P. “MicroRNAs: Target Recognition and Regulatory Functions.” Cell 136, no. 2 (January 2009): 215–233. © 2009 Elsevier Inc.
Version
Final published version
Abstract
MicroRNAs (miRNAs) are endogenous ∼23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on both the expression and evolution of protein-coding genes.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Whitehead Institute for Biomedical Research
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.cell.2009.01.002
