Diamond rotors
Name
nihms-1928974.pdf
Description
Accepted version
Size
1.43 MB
Format
Adobe PDF
Checksum (MD5)
50f2a07da7c4c6f53b49f861768e3cf4
Author(s)
Golota, Natalie C
Fredin, Zachary P
Banks, Daniel P
Preiss, David
Bahri, Salima
Patil, Prashant
Langford, William K
Blackburn, Camron L
Strand, Erik
Michael, Brian
Date Issued
July 2023
Journal
Journal of Magnetic Resonance
Publisher
Elsevier BV
Version
Author's final manuscript
Abstract
The resolution of magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectra remains bounded by the spinning frequency, which is limited by the material strength of MAS rotors. Since diamond is capable of withstanding 1.5–2.5x greater MAS frequencies, compared to state-of-the art zirconia, we fabricated rotors from single crystal diamond. When combined with bearings optimized for spinning with helium gas, diamond rotors could achieve the highest MAS frequencies to date. Furthermore, the excellent microwave transmission properties and thermal conductivity of diamond could improve sensitivity enhancements in dynamic nuclear polarization (DNP) experiments. The fabrication protocol we report involves novel laser micromachining and produced rotors that presently spin at ωr/2π = 111.000 ± 0.004 kHz, with stable spinning up to 124 kHz, using N2 gas as the driving fluid. We present the first proton-detected 13C/15N MAS spectra recorded using diamond rotors, a critical step towards studying currently inaccessible ex-vivo protein samples with MAS NMR. Previously, the high aspect ratio of MAS rotors (~10:1) precluded fabrication of MAS rotors from diamond.
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivatives
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.jmr.2023.107475
