7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
Author(s)
Yesilaltay, Ayce
Alternative Title
A Love-Hate Relationship: Cholesterol in Health and Disease
Date Issued
December 2005
Abstract
In this class, we will examine cholesterol's role in the cell and in the body as a whole, from its function as a structural component of the membrane to its function in signaling. We will discuss mechanisms of cholesterol sensing, mechanisms of feedback regulation in cells, cholesterol in the brain, cholesterol in the circulation, 'good cholesterol' and 'bad cholesterol,' cholesterol-related human disorders, and the drugs that deal with some of these disorders. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
cholesterol
biosynthesis
LDL
HDL
Smith-Lemli-Opitz Syndrome
uptake
endocytosis
hypercholesterolemia
atherosclerosis
plaque
statins
HMG-CoA
ezetimibe
heart attack
lipoprotein
Fibrates
receptor
alzheimer's
MIT Department
Massachusetts Institute of Technology. Department of Biology
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