Dynamic cell cycle–dependent phosphorylation modulates CENP-L–CENP-N centromere recruitment
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mbc.e22-06-0239.pdf
Description
Published version
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7.57 MB
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Adobe PDF
Checksum (MD5)
05e51e0fa401cc652466076dd01a79aa
Author(s) •
Navarro, Alexandra P
Cheeseman, Iain M
Date Issued
2022
Journal
Molecular Biology of the Cell
Publisher
American Society for Cell Biology (ASCB)
Citation
Navarro, Alexandra P and Cheeseman, Iain M. 2022. "Dynamic cell cycle–dependent phosphorylation modulates CENP-L–CENP-N centromere recruitment." Molecular Biology of the Cell, 33 (10).
Version
Final published version
Abstract
Despite being constitutively localized to centromeres, the DNA proximal components of the kinetochore undergo substantial remodeling throughout the cell cycle. We highlight the role of cell cycle-dependent phosphorylation in regulating the interactions and localization of the CENP-LN complex.
MIT Department
Massachusetts Institute of Technology. Department of Biology
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1091/MBC.E22-06-0239