Triggered optical coherence tomography for capturing rapid periodic motion
Name
Chang-2011-Triggered optical coherence.pdf
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6.85 MB
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Author(s)
Chang, Ernest W.
Kobler, James B.
Yun, Seok Hyun (Andy)
Date Issued
July 2011
Journal
Scientific Reports
Publisher
Nature Publishing Group
Citation
Chang, Ernest W., James B. Kobler, and Seok H. Yun. “Triggered Optical Coherence Tomography for Capturing Rapid Periodic Motion.” Sci. Rep. 1 (July 28, 2011).
Version
Final published version
Abstract
Quantitative cross-sectional imaging of vocal folds during phonation is potentially useful for diagnosis and treatments of laryngeal disorders. Optical coherence tomography (OCT) is a powerful technique, but its relatively low frame rates makes it challenging to visualize rapidly vibrating tissues. Here, we demonstrate a novel method based on triggered laser scanning to capture 4-dimensional (4D) images of samples in motu at audio frequencies over 100 Hz. As proof-of-concept experiments, we applied this technique to imaging the oscillations of biopolymer gels on acoustic vibrators and aerodynamically driven vibrations of the vocal fold in an ex vivo calf larynx model. Our results suggest that triggered 4D OCT may be useful in understanding and assessing the function of vocal folds and developing novel treatments in research and clinical settings.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1038/srep00048
