Dissecting the complex landscape of neuroinflammation at single-cell resolution
Author(s) •
Raju, Ravikiran M.
Tsai, Li-Huei
Alternative Title
The complexity of neuroinflammation at single-cell resolution
Date Issued
March 2019
Journal
Nature Reviews Neurology
Publisher
Springer Science and Business Media LLC
Citation
Raju, Ravikiran M., and Li-Huei Tsai. "The complexity of neuroinflammation at single-cell resolution." Nature Reviews Neurology 15, 5 (May 2019): 249–250 © 2019 Springer Nature Limited
Version
Author's final manuscript
Abstract
A new study, using a mouse model of multiple sclerosis, applied single-cell RNA sequencing to determine how immune cells in the CNS respond during inflammation. In addition to highlighting novel subtypes of cells that evolve over the course of disease, the findings have important implications for developing targeted therapies for inflammatory demyelinating diseases. Keyword: brain; experimental models of disease; multiple sclerosis
MIT Department
Picower Institute for Learning and Memory
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1103/10.1038/s41582-019-0165-5