7.341 Designer Immunity: Lessons in Engineering the Immune System, Spring 2014
Author(s)
Szeto, Gregory
Tokatlian, Talar
Alternative Title
Designer Immunity: Lessons in Engineering the Immune System
Date Issued
June 2014
Abstract
The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
immune system
immunoengineering
vaccines
immunotherapies
systems immunology
multivariate profiling
regulatory network analyses
vaccine design
immunomodulation
autoimmunity
vaccine carriers
tolerogenic particle vaccines
pathogen-mimicking
lipid nanoparticle vaccines
MIT Department
Massachusetts Institute of Technology. Department of Biology
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