Whispering photons : on-chip biophotonic integrated circuits for point-of-care diagnostics
Name
1120126896-MIT.pdf
Size
15.3 MB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Singh, Robin,Ph. D.Massachusetts Institute of Technology.
Advisor(s)
Brian W. Anthony and Anuradha Murthy Agarwal.
Alternative Title
On-chip biophotonic integrated circuits for point-of-care diagnostics
Date Issued
2018
Publisher
Massachusetts Institute of Technology
Abstract
The pressure of increasing service demands and improving turnaround times of results in healthcare industry require the development of more rapid, point-of-care and personalized diagnostic tools. Light is ubiquitous in biology and offers various elegant solutions for diagnostic, therapies and theranostic applications. At present, there is not a single biomedical application where optical components are not applied. If we can come up with a framework that can miniaturize these optical components on a chip, it can offer various advantages in terms of scalability, portability, cost and improved performance for real-time monitoring and bedside treatment. On these lines, we propose bio-photonic integrated circuits (Bio-PICs) for point-of-care diagnostics. These circuits rely on moving photons in photonic waveguides (similar to electrons in your electronic chips) to provide on-chip sensing solution. Specifically, we present Bio-PICs for aerosol spectroscopy, blood coagulometry, and TB breath analyzer test.
Description
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2018
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 115-121).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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