Direct Electrochemical Carboxylation of Benzylic C–N Bonds with Carbon Dioxide
Name
ACS catalysis manuscript-clean.pdf
Description
Accepted version
Size
668.61 KB
Format
Adobe PDF
Checksum (MD5)
a744eb0cc47b851bc05502f9732e7b7f
Author(s)
Yang, Dengtao
Zhu, Minghui
Schiffer, Zachary J.
Williams, Kindle
Song, Xiaojie
Liu, Xiaohui
Manthiram, Karthish
Date Issued
April 2019
Journal
ACS Catalysis
Publisher
American Chemical Society (ACS)
Citation
Yang, Deng-Tao et al. "Direct Electrochemical Carboxylation of Benzylic C–N Bonds with Carbon Dioxide." ACS Catalysis 9, 5 (April 2019): 4699–4705 © 2019 American Chemical Society
Version
Author's final manuscript
Abstract
We report a direct and efficient electrochemical carboxylation of benzylic C-N bonds with CO₂ at room temperature. The reaction has been successfully applied to both primary and secondary benzylic C-N bonds with the compatibility of a variety of functional groups. This procedure does not require stoichiometric metals, external reducing agents, or sacrificial anodes, making column chromatography unnecessary for product purification. Differential electrochemical mass spectrometry (DEMS) was used to elucidate key intermediates of the electrocarboxylation reaction.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/acscatal.9b00818
