Smart nanosystems: Bio-inspired technologies that interact with the host environment
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Kwon-2015-Smart nanosystems_ B.pdf
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Author(s)
Kwon, Ester
Lo, Justin H.
Bhatia, Sangeeta N
Date Issued
November 2015
Journal
Proceedings of the National Academy of Sciences
Publisher
National Academy of Sciences (U.S.)
Citation
Kwon, Ester J., Justin H. Lo, and Sangeeta N. Bhatia. “Smart Nanosystems: Bio-Inspired Technologies That Interact with the Host Environment.” Proc Natl Acad Sci USA 112, no. 47 (November 23, 2015): 14460–14466. © 2016 National Academy of Sciences.
Version
Final published version
Abstract
Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Koch Institute for Integrative Cancer Research at MIT
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1073/pnas.1508522112
