Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates
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Buchwald_Pd-Catalyzed cross.pdf
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Author(s)
Dooleweerdt, Karin
Fors, Brett P.
Buchwald, Stephen Leffler
Date Issued
April 2010
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Dooleweerdt, Karin, Brett P. Fors, and Stephen L. Buchwald. “Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates.” Organic Letters 12.10 (2010): 2350–2353.
Version
Author's final manuscript
Abstract
A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ol100720x
