Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?
Name
IJB-V10No1-p408-410.pdf
Description
Main article
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339.81 KB
Format
Adobe PDF
Checksum (MD5)
ce188d2e100509537147a17804614c85
Author(s)
Ghosal, Anubrata
Date Issued
January 2017
Journal
International Journal of Biosciences (IJB)
Publisher
International Network for Natural Sciences (INNSPUB)
Citation
Ghosal, Anubrata. “Is Antibacterial PNA the Answer for Combating Multidrug Resistant Bacterial Infections?” International Journal of Biosciences (IJB) 10, no. 1 (January 31, 2017): 408-410.
Version
Final published version
Abstract
The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90’s as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains.
MIT Department
Massachusetts Institute of Technology. Department of Biology
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.12692/ijb/10.1.408-410
