Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity
Name
mBio.00455-21.pdf
Description
Published version
Size
1.86 MB
Format
Adobe PDF
Checksum (MD5)
3fa56cefe87751014f22c0c4590937a4
Author(s)
Latka, Agnieszka
Lemire, Sebastien
Grimon, Dennis
Dams, Dorien
Maciejewska, Barbara
Lu, Timothy
Drulis-Kawa, Zuzanna
Briers, Yves
Date Issued
2021
Journal
mBio
Publisher
American Society for Microbiology
Citation
Latka, Agnieszka, Lemire, Sebastien, Grimon, Dennis, Dams, Dorien, Maciejewska, Barbara et al. 2021. "Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity." mBio, 12 (3).
Version
Final published version
Abstract
The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.
MIT Department
Massachusetts Institute of Technology. Synthetic Biology Center
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Research Laboratory of Electronics
Singapore-MIT Alliance in Research and Technology (SMART)
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1128/MBIO.00455-21
