New Insights into Genome Structure: Genes of a Feather Stick Together
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Young_New insights.pdf
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Author(s) •
Hnisz, Denes
Young, Richard A.
Date Issued
September 2017
Journal
Molecular Cell
Publisher
Elsevier BV
Citation
Hnisz, Denes and Richard A. Young. “New Insights into Genome Structure: Genes of a Feather Stick Together.” Molecular Cell 67, 5 (September 2017): 730–731 © 2017 Elsevier Inc
Version
Author's final manuscript
Abstract
DNA structuring proteins such as CTCF facilitate DNA loop formation and are presumed to be among the major determinants of eukaryotic genome structure. Recent studies, including Rowley et al. (2017), suggest that gene activation and repression play fundamentally important roles in structuring the genome independently of CTCF.
MIT Department
Massachusetts Institute of Technology. Department of Biology
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Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/J.MOLCEL.2017.08.023