Synthesis of colloidal microgels using oxygen-controlled flow lithography
Name
Doyle_Synthesis of colloidal.pdf
Size
718.67 KB
Format
Adobe PDF
Checksum (MD5)
a67bf3818196a1d4f9ae48ea4349946c
Author(s)
An, Harry
Eral, Huseyin Burak
Chen, Lynna
Chen, Michelle B
Doyle, Patrick S
Date Issued
July 2014
Journal
Soft Matter
Publisher
Royal Society of Chemistry
Citation
An, Harry Z. et al. “Synthesis of Colloidal Microgels Using Oxygen-Controlled Flow Lithography.” Soft Matter 10.38 (2014): 7595–7605.
Version
Author's final manuscript
Abstract
We report a synthesis approach based on stop-flow lithography (SFL) for fabricating colloidal microparticles with any arbitrary 2D-extruded shape. By modulating the degree of oxygen inhibition during synthesis, we achieved previously unattainable particle sizes. Brownian diffusion of colloidal discs in bulk suggests the out-of-plane dimension can be as small as 0.8 μm, which agrees with confocal microscopy measurements. We measured the hindered diffusion of microdiscs near a solid surface and compared our results to theoretical predictions. These colloidal particles can also flow through physiological microvascular networks formed by endothelial cells undergoing vasculogensis under minimal hydrostatic pressure (∼5 mm H2O). This versatile platform creates future opportunities for on-chip parametric studies of particle geometry effects on particle passage properties, distribution and cellular interactions.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1039/c4sm01400f
