Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles
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Hammond_Scalable manufacture.pdf
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1.34 MB
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Author(s)
Herlihy, Kevin P.
Deng, Zhou J.
Chu, Kevin S.
Bowerman, Charles J.
DeSimone, Joseph M.
Morton, Stephen Winford
Shopsowitz, Kevin
Hammond, Paula T
Date Issued
July 2013
Journal
Advanced Materials
Publisher
Wiley Blackwell
Citation
Morton, Stephen W., Kevin P. Herlihy, Kevin E. Shopsowitz, Zhou J. Deng, Kevin S. Chu, Charles J. Bowerman, Joseph M. DeSimone, and Paula T. Hammond. “Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles.” Advanced Materials 25, no. 34 (July 1, 2013): 4707–4713.
Version
Author's final manuscript
Abstract
Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1002/adma.201302025
