Thalamic activity that drives visual cortical plasticity
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Bear-2009-Thalamic activity that drives.pdf
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543.12 KB
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Author(s)
Linden, Monica L.
Heynen, Arnold J.
Haslinger, Robert Heinz
Bear, Mark
Date Issued
April 2009
Journal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Linden, Monica L. et al. “Thalamic Activity That Drives Visual Cortical Plasticity.” Nature Neuroscience 12.4 (2009): 390–392.
Version
Author's final manuscript
Abstract
Manipulations of activity in one retina can profoundly affect binocular connections in the visual cortex. Retinal activity is relayed to the cortex by the dorsal lateral geniculate nucleus (dLGN). We compared the qualities and amount of activity in the dLGN following monocular eyelid closure and monocular retinal inactivation in awake mice. Our findings substantially alter the interpretation of previous studies and define the afferent activity patterns that trigger cortical plasticity.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Picower Institute for Learning and Memory
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Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1038/nn.2284
