Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins
Name
d0an00299b.pdf
Description
Published version
Size
1.54 MB
Format
Adobe PDF
Checksum (MD5)
af328ff152ac5335a26d3e02b1849600
Author(s)
Sung, Ki-Joo
Jabbour Al Maalouf, Yara
Johns, Quinlan R.
Miller, Eric Alexander
Sikes Johnson, Hadley
Date Issued
March 2020
Journal
Analyst
Publisher
Royal Society of Chemistry (RSC)
Citation
Sung, Ki-Joo, et al. "Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins." Analyst, 145 (2020): 2515-2519. © The Royal Society of Chemistry 2020.
Version
Final published version
Abstract
Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Creative Commons Attribution Noncommercial 3.0 unported license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1039/d0an00299b
