Place-cell capacity and volatility with grid-like inputs
Name
elife-62702-v3.pdf
Description
Published version
Size
7.73 MB
Format
Adobe PDF
Checksum (MD5)
790612e7942aba70b925f84626505948
Author(s)
Yim, Man Yi
Sadun, Lorenzo A
Fiete, Ila R
Taillefumier, Thibaud
Date Issued
2021
Journal
eLife
Publisher
eLife Sciences Publications, Ltd
Citation
Yim, Man Yi, Sadun, Lorenzo A, Fiete, Ila R and Taillefumier, Thibaud. 2021. "Place-cell capacity and volatility with grid-like inputs." eLife, 10.
Version
Final published version
Abstract
What factors constrain the arrangement of the multiple fields of a place cell? By modeling place cells as perceptrons that act on multiscale periodic grid-cell inputs, we analytically enumerate a place cell’s repertoire – how many field arrangements it can realize without external cues while its grid inputs are unique – and derive its capacity – the spatial range over which it can achieve any field arrangement. We show that the repertoire is very large and relatively noise-robust. However, the repertoire is a vanishing fraction of all arrangements, while capacity scales only as the sum of the grid periods so field arrangements are constrained over larger distances. Thus, grid-driven place field arrangements define a large response scaffold that is strongly constrained by its structured inputs. Finally, we show that altering grid-place weights to generate an arbitrary new place field strongly affects existing arrangements, which could explain the volatility of the place code.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
McGovern Institute for Brain Research at MIT
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.7554/ELIFE.62702
