From bench to bedside : impact of conflict-of-interest restrictions at academic medical centers on clinical trials
Name
829680663-MIT.pdf
Description
Full printable version
Size
4.31 MB
Format
Adobe PDF
Checksum (MD5)
5751a9e52ebaaee03b5e57401fd8bd5d
Author(s)
Campbell, Elyssa Sarah
Advisor(s)
Fiona Murray and Anthony Sinskey.
Alternative Title
Impact of conflict-of-interest restrictions at academic medical centers on clinical trials
Date Issued
2012
Publisher
Massachusetts Institute of Technology
Abstract
Successful translation of scientific discovery into new medicines is most successful with collaboration between academics - scientists and physicians - and industry. In recent years, there has been increasing concern at academic medical centers about the impact of relationships with industry on patient care and student education. This has generally resulted in more stringent conflict-of-interest rules. This paper seeks to better understand the impact of these conflict-of-interest rules. In the first part, it explores research to-date on the importance of relationships between industry and academia and discusses some of the concerns that have arisen. In the second part, this relationship is better characterized with clinical trial data. The findings suggest that there is a strong trend towards schools with higher conflict-of-interest rules having fewer clinical trials. This suggests that although there may be benefits to stricter regulation, there are trade-offs in terms of clinical translation.
Description
Thesis (S.M. in Health Sciences and Technology)--Harvard-MIT Program in Health Sciences and Technology, 2012.
"September 2012." Cataloged from PDF version of thesis.
Includes bibliographical references (p. 37-40).
Subjects
Harvard--MIT Program in Health Sciences and Technology.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
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