Putting Two Heads Together to Unwind DNA
Name
Bell_Putting two.pdf
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526.64 KB
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Checksum (MD5)
91a7216f6f4b19e89499299ff84723e0
Author(s)
Takara, Thomas J.
Takara,Thomas J.
Bell, Stephen P
Date Issued
November 2009
Journal
Cell
Publisher
Elsevier B.V.
Citation
Takara, Thomas J., and Stephen P. Bell. “Putting Two Heads Together to Unwind DNA.” Cell 139, no. 4 (November 2009): 652-654. http://dx.doi.org/10.1016/j.cell.2009.10.037. © 2009 Elsevier Inc.
Version
Final published version
Abstract
The loading of replicative helicases onto DNA is tightly regulated in all organisms, yet the molecular mechanisms for this event remain poorly defined. Remus et al. (2009) provide important insights into helicase loading in eukaryotes, showing that the Mcm2–7 replicative helicase encircles double-stranded DNA as head-to-head double hexamers.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1016/j.cell.2009.10.037
