Emerging nanotechnology approaches for HIV/AIDS treatment and prevention
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nihms180336.pdf
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Accepted version
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1.15 MB
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Author(s) • • • • • • • •
Mamo, Tewodros
Moseman, E Ashley
Kolishetti, Nagesh
Salvador-Morales, Carolina
Shi, Jinjun
Kuritzkes, Daniel R
Langer, Robert S
Andrian, Ulrich von
Farokhzad, Omid C
Date Issued
2010
Journal
Nanomedicine: Nanotechnology, Biology, and Medicine
Publisher
Future Medicine Ltd
Citation
Mamo, T., et al. "Emerging Nanotechnology Approaches for Hiv/Aids Treatment and Prevention." Nanomedicine 5 2 (2010): 269-85.
Version
Author's final manuscript
Abstract
Currently, there is no cure and no preventive vaccine for HIV/AIDS. Combination antiretroviral therapy has dramatically improved treatment, but it has to be taken for a lifetime, has major side effects and is ineffective in patients in whom the virus develops resistance. Nanotechnology is an emerging multidisciplinary field that is revolutionizing medicine in the 21st century. It has a vast potential to radically advance the treatment and prevention of HIV/AIDS. In this review, we discuss the challenges with the current treatment of the disease and shed light on the remarkable potential of nanotechnology to provide more effective treatment and prevention for HIV/AIDS by advancing antiretroviral therapy, gene therapy, immunotherapy, vaccinology and microbicides. © 2010 Future Medicine Ltd.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Biological Engineering
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.2217/nnm.10.1