dbOTU3: A new implementation of distribution-based OTU calling
Name
journal.pone.0176335.pdf
Size
1.8 MB
Format
Adobe PDF
Checksum (MD5)
b066fac842e4623d9ac03c4ff1155d25
Author(s)
Olesen, Scott Wilder
Duvallet, Claire
Alm, Eric J
Date Issued
May 2017
Journal
PLOS ONE
Publisher
Public Library of Science
Citation
Olesen, Scott W. et al. “dbOTU3: A New Implementation of Distribution-Based OTU Calling.” Edited by Jonathan H. Badger. PLOS ONE 12, 5 (May 2017): e0176335 © 2017 Olesen et al
Version
Original manuscript
Abstract
Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences' distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers.
MIT Department
Institute for Medical Engineering and Science
Massachusetts Institute of Technology. Department of Biological Engineering
Terms of Use
Creative Commons Attribution 4.0 International License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1371/JOURNAL.PONE.0176335
