Recording and Quantifying C. elegans Behavior
Name
Pokala_Flavell_TrackingArticle[8].pdf
Description
Accepted version
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163.66 KB
Format
Adobe PDF
Checksum (MD5)
d90afb87eb72d51291c661d6100e71c3
Author(s) •
Pokala, Navin
Flavell, Steven W
Date Issued
2022
Publisher
Springer US
Citation
Pokala, Navin and Flavell, Steven W. 2022. "Recording and Quantifying C. elegans Behavior." 2468.
Version
Author's final manuscript
Abstract
Studies of C. elegans behavior have been crucial in identifying genetic pathways that control nervous system development and function, as well as basic principles of neural circuit function. Modern analysis of C. elegans behavior commonly relies on video recordings of animals, followed by automated image analysis and behavior quantification. Here, we describe two methods for recording and quantifying C. elegans behavior: a single-worm tracking approach that provides high-resolution behavioral data for individual animals and a multi-worm tracking approach that allows for quantification of the behavior of many animals in parallel. These approaches should be useful to a wide range of researchers studying the nervous system and behavior of C. elegans.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1007/978-1-0716-2181-3_20