SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polymorphs: advantage of heterogeneous nucleation
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c8ce00272j.pdf
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2.14 MB
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9296480f3c067a3640a37530610c47d4
Author(s)
Bolla, Geetha
Myerson, Allan S.
Date Issued
March 2018
Journal
CrystEngComm
Publisher
Royal Society of Chemistry (Great Britain)
Citation
Bolla, Geetha, and Allan S. Myerson. “SURMOF Induced Polymorphism and Crystal Morphological Engineering of Acetaminophen Polymorphs: Advantage of Heterogeneous Nucleation.” CrystEngComm 20, no. 15 (2018): 2084–2088.
Version
Final published version
Abstract
© 2018 The Royal Society of Chemistry. Self-assembled monolayers are extended to SURMOFs as template hetero surfaces using a basic HKUST-1 MOF. The concept of MOF induced polymorphism with morphological engineering adapted to crystal engineering has shown to have the advantage of heterogeneous nucleation. The substrates are used to study the nucleation and growth of acetaminophen, and have resulted in metastable polymorphs which are of a desirable form with block morphology.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
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Creative Commons Attribution 3.0 Unported license
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DOI of Published Version
https://doi.org/10.1039/c8ce00272j
