Optical tweezer measurements of asymptotic nonlinearities in complex fluids
Name
PhysRevE.104.064604.pdf
Description
Published version
Size
753.65 KB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Gupta, Satish Kumar
Lennon, Kyle R.
Joens, Mary A.
Bandi, Hari
Van Galen, Martijn
Han, YuLong
Tang, Wenhui
Li, Yiwei
Wasserman, Steven Charles
Swan, James W.
Date Issued
December 7, 2021
Journal
Physical Review E
Publisher
American Physical Society (APS)
Citation
Gupta, Satish Kumar, Lennon, Kyle R., Joens, Mary A., Bandi, Hari, Van Galen, Martijn et al. 2021. "Optical tweezer measurements of asymptotic nonlinearities in complex fluids." Physical Review E, 104 (6).
Version
Final published version
Abstract
This article presents micro-medium-amplitude oscillatory shear (μMAOS), a method to measure the frequency-dependent micromechanical properties of soft materials in the asymptotically nonlinear regime using optical tweezers. We have developed a theoretical framework to extract these nonlinear mechanical properties of the material from experimental measurements and also proposed a physical interpretation of the third-order nonlinearities measured in single-tone oscillatory tests. We validate the method using a well-characterized surfactant solution of wormlike micelles, and subsequently employ this technique to demonstrate that the cytoplasm of a living cell undergoes strain softening and shear thinning when locally subjected to weakly nonlinear oscillatory deformations.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Operations Research Center
Massachusetts Institute of Technology. Department of Biological Engineering
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DOI of Published Version
https://doi.org/10.1103/physreve.104.064604
