Hydrogel bioelectronics
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c8cs00595h.pdf
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8.68 MB
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Adobe PDF
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Author(s) • •
Yuk, Hyunwoo
Lu, Baoyang
Zhao, Xuanhe
Date Issued
November 2018
Journal
Chemical Society Reviews
Publisher
The Royal Society of Chemistry
Citation
Yuk, Hyunwoo, Baoyang Lu, and Xuanhe Zhao. “Hydrogel Bioelectronics.” Chemical Society Reviews (November 2019). © 2018 The Royal Society of Chemistry
Version
Final published version
Abstract
Bioelectronic interfacing with the human body including electrical stimulation and recording of neural activities is the basis of the rapidly growing field of neural science and engineering, diagnostics, therapy, and wearable and implantable devices. Owing to intrinsic dissimilarities between soft, wet, and living biological tissues and rigid, dry, and synthetic electronic systems, the development of more compatible, effective, and stable interfaces between these two different realms has been one of the most daunting challenges in science and technology. Recently, hydrogels have emerged as a promising material candidate for the next-generation bioelectronic interfaces, due to their similarities to biological tissues and versatility in electrical, mechanical, and biofunctional engineering. In this review, we discuss (i) the fundamental mechanisms of tissue-electrode interactions, (ii) hydrogels' unique advantages in bioelectrical interfacing with the human body, (iii) the recent progress in hydrogel developments for bioelectronics, and (iv) rational guidelines for the design of future hydrogel bioelectronics. Advances in hydrogel bioelectronics will usher unprecedented opportunities toward ever-close integration of biology and electronics, potentially blurring the boundary between humans and machines.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Creative Commons Attribution Noncommercial 3.0 unported license
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DOI of Published Version
https://doi.org/10.1039/c8cs00595h