Acoustic Voice and Speech Biomarkers of Treatment Status during Hospitalization for Acute Decompensated Heart Failure
Name
applsci-13-01827.pdf
Size
1.23 MB
Format
Adobe PDF
Checksum (MD5)
3950e6809c0695c5981331d972f32235
Author(s)
Murton, Olivia M.
Dec, G. William
Hillman, Robert E.
Majmudar, Maulik D.
Steiner, Johannes
Guttag, John V.
Mehta, Daryush D.
Date Issued
January 31, 2023
Publisher
Multidisciplinary Digital Publishing Institute
Citation
Applied Sciences 13 (3): 1827 (2023)
Version
Final published version
Abstract
This study investigates acoustic voice and speech features as biomarkers for acute decompensated heart failure (ADHF), a serious escalation of heart failure symptoms including breathlessness and fatigue. ADHF-related systemic fluid accumulation in the lungs and laryngeal tissues is hypothesized to affect phonation and respiration for speech. A set of daily spoken recordings from 52 patients undergoing inpatient ADHF treatment was analyzed to identify voice and speech biomarkers for ADHF and to examine the trajectory of biomarkers during treatment. Results indicated that speakers produce more stable phonation, a more creaky voice, faster speech rates, and longer phrases after ADHF treatment compared to their pre-treatment voices. This project builds on work to develop a method of monitoring ADHF using speech biomarkers and presents a more detailed understanding of relevant voice and speech features.
MIT Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3390/app13031827
