Re-strengthening demineralized bone via tannin-iron crosslinking
Name
1149014693-MIT.pdf
Size
3.01 MB
Format
Adobe PDF
Checksum (MD5)
1156684b044b78c268a3cec9dbfcf476
Author(s)
Hart, Sawyer(Sawyer H.)
Advisor(s)
Niels Holten-Andersen.
Date Issued
2019
Publisher
Massachusetts Institute of Technology
Abstract
As the world population continues to age, the social and economic impacts resulting from osteoporosis will continue to rise. New treatments for the disease are needed now more than ever. Using tannin iron complexes we show that thin film deposition of the complexes are not only possible but effective at strengthening demineralized bone. Furthermore we show that by taking advantage of newly discovered tris-complexes that are able to form between tannic acid and ferrous iron ion in solution, the strengthening ability of the film increases dramatically. Specifically, we show that tannin iron tris-complex coating results in a 1062% increase in the flexural modulus for fully hydrated and demineralized bone.
Description
Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references (pages [30]-[31]).
Subjects
Materials Science and Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
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