GENCODE reference annotation for the human and mouse genomes
Name
gky955.pdf
Description
Published version
Size
1.07 MB
Format
Unknown
Checksum (MD5)
8ebbc29975cbf312219fc4423d61ff7c
Author(s)
Frankish, Adam
Diekhans, Mark
Ferreira, Anne-Maud
Johnson, Rory
Jungreis, Irwin
Loveland, Jane
Mudge, Jonathan M
Sisu, Cristina
Wright, James
Armstrong, Joel
Date Issued
October 2018
Journal
Nucleic Acids Research
Publisher
Oxford University Press (OUP)
Version
Final published version
Abstract
© 2018 The Author(s). The accurate identification and description of the genes in the human and mouse genomes is a fundamental requirement for high quality analysis of data informing both genome biology and clinical genomics. Over the last 15 years, the GENCODE consortium has been producing reference quality gene annotations to provide this foundational resource. The GENCODE consortium includes both experimental and computational biology groups who work together to improve and extend theGENCODE gene annotation. Specifically, we generate primary data, create bioinformatics tools and provide analysis to support the work of expert manual gene annotators and automated gene annotation pipelines. In addition, manual and computational annotation workflows use any and all publicly available data and analysis, along with the research literature to identify and characterise gene loci to the highest standard. GENCODE gene annotations are accessible via the Ensembl and UCSC Genome Browsers, the Ensembl FTP site, Ensembl Biomart, Ensembl Perl and REST APIs as well as https://www.gencodegenes.org.
MIT Department
Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1093/nar/gky955
