Assessment of in vitro engineered microvascular networks and their application in the treatment of chronic wounds

Thumbnail Image
Download
Name

228504392-MIT.pdf

Description
Full printable version
Size

4.06 MB

Format

Adobe PDF

Checksum (MD5)

7f893fd7dd050a0717c08d0ae466116a

Author(s)
King, Connie Hong-Yee
Advisor(s)
Mark Keegan and Darrell J. Irvine.
Date Issued
2007
Publisher
Massachusetts Institute of Technology
Abstract
As the number of individuals suffering from tissue loss and end-stage organ failure continues to grow, researchers are turning to tissue engineering to provide better methods of treatment. The field, however, still faces many technical challenges that are limiting its applications. One challenge faced in engineering more complex tissues and organs is the need for inherent microvasculature to supply the tissue with nutrients and oxygen. Researchers at The Charles Stark Draper Laboratory have developed a method for engineering microvascular networks in vitro using various microfabrication techniques. This paper discusses the current state of the research and technical challenges to overcome before commercializing the technology. The feasibility of using the networks in the nearer term application of treating chronic wounds will also be assessed, and a potential business strategy will be laid out.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.
"September 2007."
Includes bibliographical references (p. 67-72).
Subjects
Materials Science and Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
Persistent DSpace Link
PrivacyPermissionsAccessibilityContact us
Notify us about copyright concerns.