A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
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Author(s) • • • • • • • • •
Madisen, Linda
Mao, Tianyi
Koch, Henner
Zhuo, Jia-min
Berenyi, Antal
Fujisawa, Shigeyoshi
Hsu, Yun-Wei A
Garcia, Alfredo J
Gu, Xuan
Zanella, Sebastien
Date Issued
March 2012
Journal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Madisen, Linda et al. “A Toolbox of Cre-Dependent Optogenetic Transgenic Mice for Light-Induced Activation and Silencing.” Nature Neuroscience 15.5 (2012): 793–802.
Version
Author's final manuscript
Abstract
We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within
some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.
MIT Department
Massachusetts Institute of Technology. Media Laboratory
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1038/nn.3078