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  4. A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

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Author(s)
Madisen, Linda
•
Mao, Tianyi
•
Koch, Henner
•
Zhuo, Jia-min
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Berenyi, Antal
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Fujisawa, Shigeyoshi
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Hsu, Yun-Wei A
•
Garcia, Alfredo J
•
Gu, Xuan
•
Zanella, Sebastien
more
Date Issued
March 2012
Journal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Madisen, Linda et al. “A Toolbox of Cre-Dependent Optogenetic Transgenic Mice for Light-Induced Activation and Silencing.” Nature Neuroscience 15.5 (2012): 793–802.
Version
Author's final manuscript
Abstract
We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.
MIT Department
Massachusetts Institute of Technology. Media Laboratory
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
http://creativecommons.org/licenses/by-nc-sa/4.0/
Persistent DSpace Link
http://hdl.handle.net/1721.1/107771
DOI of Published Version
https://doi.org/10.1038/nn.3078
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