AI-Enabled, Ultrasound-Guided Handheld Robotic Device for Femoral Vascular Access
Name
biosensors-11-00522-v2.pdf
Size
3.54 MB
Format
Adobe PDF
Checksum (MD5)
191d8b898d3f84fc274b9413ad11e014
Author(s)
Brattain, Laura J.
Pierce, Theodore T.
Gjesteby, Lars A.
Johnson, Matthew R.
DeLosa, Nancy D.
Werblin, Joshua S.
Gupta, Jay F.
Ozturk, Arinc
Wang, Xiaohong
Li, Qian
Date Issued
December 18, 2021
Publisher
Multidisciplinary Digital Publishing Institute
Citation
Biosensors 11 (12): 522 (2021)
Version
Final published version
Abstract
Hemorrhage is a leading cause of trauma death, particularly in prehospital environments when evacuation is delayed. Obtaining central vascular access to a deep artery or vein is important for administration of emergency drugs and analgesics, and rapid replacement of blood volume, as well as invasive sensing and emerging life-saving interventions. However, central access is normally performed by highly experienced critical care physicians in a hospital setting. We developed a handheld AI-enabled interventional device, AI-GUIDE (Artificial Intelligence Guided Ultrasound Interventional Device), capable of directing users with no ultrasound or interventional expertise to catheterize a deep blood vessel, with an initial focus on the femoral vein. AI-GUIDE integrates with widely available commercial portable ultrasound systems and guides a user in ultrasound probe localization, venous puncture-point localization, and needle insertion. The system performs vascular puncture robotically and incorporates a preloaded guidewire to facilitate the Seldinger technique of catheter insertion. Results from tissue-mimicking phantom and porcine studies under normotensive and hypotensive conditions provide evidence of the technique’s robustness, with key performance metrics in a live porcine model including: a mean time to acquire femoral vein insertion point of 53 ± 36 s (5 users with varying experience, in 20 trials), a total time to insert catheter of 80 ± 30 s (1 user, in 6 trials), and a mean number of 1.1 (normotensive, 39 trials) and 1.3 (hypotensive, 55 trials) needle insertion attempts (1 user). These performance metrics in a porcine model are consistent with those for experienced medical providers performing central vascular access on humans in a hospital.
MIT Department
Lincoln Laboratory
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3390/bios11120522
