Polarization sensitive optical coherence tomography of melanin provides tissue inherent contrast based on depolarization
Name
Baumann-2010-Polarization sensitive optical .pdf
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5.64 MB
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Author(s)
Baumann, Bernhard
Baumann, Stefan O.
Konegger, Thomas
Pircher, Michael
Götzinger, Erich
Sattmann, Harald
Litschauer, Marco
Hitzenberger, Christoph K.
Date Issued
February 2010
Journal
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
Publisher
Society of Photo-optical Instrumentation Engineers
Citation
Baumann, Bernhard et al. “Polarization sensitive optical coherence tomography of melanin provides tissue inherent contrast based on depolarization.” Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV. Ed. Joseph A. Izatt, James G. Fujimoto, & Valery V. Tuchin. San Francisco, California, USA: SPIE, 2010. Vol.7554, 75541M-6. ©2010 SPIE--The International Society for Optical Engineering.
Version
Final published version
Abstract
Polarization sensitive optical coherence tomography (PS-OCT) was used to investigate the polarization properties of melanin. Measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization. The results indicate that the depolarizing appearance of pigmented structures like, for instance, the retinal pigment epithelium (RPE) is likely to be caused by the melanin granules contained in these cells.
MIT Department
Massachusetts Institute of Technology. Research Laboratory of Electronics
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1117/12.843226
