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  4. 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review

30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review

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Author(s)
Bardhan, Neelkanth Manoj
Date Issued
December 2016
Journal
Journal of Materials Research
Publisher
Cambridge University Press
Citation
Bardhan, Neelkanth M. “30 Years of Advances in Functionalization of Carbon Nanomaterials for Biomedical Applications: a Practical Review.” Journal of Materials Research 32, 1 (January 2017): 107–127 © 2016 Materials Research Society
Version
Final published version
Abstract
Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However, for bio-applications, CANOMATs need to be surface-functionalized, to render them passive, non-toxic, and water-soluble. Here, we review the current state-of-the-art in the methods of functionalization of CANOMATs. In contrast to other Reviews, we present an objective analysis of the various approaches reported in the literature, using metrics such as the agent of functionalization, number of steps, and time required, the need for special instruments, effect on properties, scalability, reproducibility, and applications. Our Review offers a way for researchers to make a rational selection of the process of functionalization to best suit their desired application. This opens up new opportunities for developing targeted functionalization strategies, based on the need to excel at the above metrics.
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
Creative Commons Attribution 4.0 International License
http://creativecommons.org/licenses/by/4.0/
Persistent DSpace Link
http://hdl.handle.net/1721.1/113202
DOI of Published Version
https://doi.org/10.1557/jmr.2016.449
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