The Logic Linking Protein Acetylation and Metabolism
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Guarente_The logic.pdf
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181.26 KB
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Author(s)
Guarente, Leonard Pershing
Date Issued
August 2011
Journal
Cell Metabolism
Publisher
Elsevier
Citation
Guarente, Leonard. “The Logic Linking Protein Acetylation and Metabolism.” Cell Metabolism 14, no. 2 (August 2011): 151-153. Copyright © 2011 Elsevier Inc.
Version
Final published version
Abstract
Protein acetylation now rivals phosphorylation in frequency of occurrence but is incompletely understood. A picture is presented in which protein acetylation is linked to available energy via the NAD-dependent deacetylases. This model suggests that protein acetylation regulates metabolic strategy and also helps store energy in cells.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology)
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1016/j.cmet.2011.07.007
