A Central Role for mTOR in Lipid Homeostasis
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Sabatini_A central.pdf
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Author(s)
Lamming, Dudley W.
Sabatini, David M.
Lamming, Dudley W.
Sabatini, David
Date Issued
August 2013
Journal
Cell Metabolism
Publisher
Elsevier
Citation
Lamming, Dudley W., and David M. Sabatini. “A Central Role for mTOR in Lipid Homeostasis.” Cell Metabolism 18, no. 4 (October 2013): 465-469.
Version
Author's final manuscript
Abstract
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role of mTORC2 in lipolysis, lipogenesis, and adipogenesis.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Whitehead Institute for Biomedical Research
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/j.cmet.2013.08.002
