Synthetic biology devices as tools for metabolic engineering
Name
Shiue and Prather_BEJ_2012_unformatted.pdf
Description
Accepted version
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452.54 KB
Format
Adobe PDF
Checksum (MD5)
4a2e3da336b217280910eb4717c0c137
Author(s) •
Shiue, Eric
Prather, Kristala L
Date Issued
June 2012
Journal
Biochemical Engineering Journal
Publisher
Elsevier BV
Citation
Shiue, Eric and Kristala L. J. Prather. "Synthetic biology devices as tools for metabolic engineering." Biochemical Engineering Journal 65 (June 2012): 82-89 © 2012 Elsevier B.V.
Version
Author's final manuscript
Abstract
Metabolic engineering focuses on controlling cellular metabolism and heterologous pathway flux to maximize the production of a product of interest. In recent years, various " devices" have begun to emerge from synthetic biology which could find widespread application in the field of metabolic engineering. In this review, we describe devices from synthetic biology and discuss the difficulties that may be encountered when using these devices as tools for metabolic engineering. Keywords: Synthetic biology devices; Metabolic engineering; Process integration; Large scale cultivation; Sensors; Scale-up
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.bej.2012.04.006