Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity
Name
nihms-1016957.pdf
Description
Accepted version
Size
1.2 MB
Format
Adobe PDF
Checksum (MD5)
c76dcf68337772b3381a87d043d0ce52
Author(s)
Kang, Eun Sung
Kim, Yong-Tae
Ko, Young-Seon
Kim, Nam Hyeong
Cho, Geonhee
Huh, Yang Hoon
Kim, Ji-Hun
Nam, Jiyoung
Thach, Trung Thanh
Youn, David
Date Issued
May 29, 2018
Journal
ACS Nano
Publisher
American Chemical Society
Citation
Kang, Eun Sung et al. "Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity." ACS Nano 12, 7 (2018): 6554-6562 © 2018 Publisher
Version
Author's final manuscript
Abstract
Biomaterials derived via programmable supramolecular protein assembly provide a viable means of constructing precisely defined structures. Here, we present programmed superstructures of AuPt nanoparticles (NPs) on carbon nanotubes (CNTs) that exhibit distinct electrocatalytic activities with respect to the nanoparticle positions via rationally modulated peptide-mediated assembly. De novo designed peptides assemble into six-helix bundles along the CNT axis to form a suprahelical structure. Surface cysteine residues of the peptides create AuPt-specific nucleation site, which allow for precise positioning of NPs onto helical geometries, as confirmed by 3-D reconstruction using electron tomography. The electrocatalytic model system, i.e., AuPt for oxygen reduction, yields electrochemical response signals that reflect the controlled arrangement of NPs in the intended assemblies. Our design approach can be expanded to versatile fields to build sophisticated functional assemblies. Keywords: supramolecular protein self-assembly; artificialy designed peptide; nanoparticle superstructure; electron tomography; peptide-based superstructure 3-D reconstruction; peptide-based catalyst; electrocatalytic oxygen reduction
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/acsnano.8b01146
