Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
Name
Rowlands_2019_J._Phys._D__Appl._Phys._52_264001.pdf
Description
Published version
Size
3.7 MB
Format
Adobe PDF
Checksum (MD5)
207da65bd71bf3135c722f67c431426c
Author(s) • • • • • •
Rowlands, Christopher J.
Bruns, Oliver T.
Franke, Daniel
Fukamura, Dai
Jain, Rakesh K.
Bawendi, Moungi G.
So, Peter T.C.
Date Issued
April 2019
Journal
Journal of Physics D: Applied Physics
Publisher
IOP Publishing
Citation
Rowlands, Christopher J. et al. "Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications." Journal of Physics D: Applied Physics 52, 26 (Apr. 2019): doi 10.1088/1361-6463/AB16B4 ©2019 Author(s)
Version
Final published version
Abstract
© 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution 3.0 unported license
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DOI of Published Version
https://doi.org/10.1088/1361-6463/AB16B4