Towards a Human Cell Atlas: Taking Notes from the Past
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1-s2.0-S0168952521000767-main.pdf
Description
Published version
Size
663.08 KB
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Unknown
Checksum (MD5)
b06c30be3961efbae43850d8c2f19512
Author(s)
Lindeboom, Rik GH
Regev, Aviv
Teichmann, Sarah A
Date Issued
2021
Journal
Trends in Genetics
Publisher
Elsevier BV
Version
Final published version
Abstract
Comprehensively characterizing the cellular composition and organization of tissues has been a long-term scientific challenge that has limited our ability to study fundamental and clinical aspects of human physiology. The Human Cell Atlas (HCA) is a global collaborative effort to create a reference map of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease. Many aspects of the HCA are analogous to the Human Genome Project (HGP), whose completion presents a major milestone in modern biology. To commemorate the HGP's 20-year anniversary of completion, we discuss the launch of the HCA in light of the HGP, and highlight recent progress by the HCA consortium.
MIT Department
Klarman Cell Observatory (Broad Institute)
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1016/j.tig.2021.03.007
