A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention
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nihms842081.pdf
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Accepted version
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517.81 KB
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Author(s) • • • •
Lee, Young-Ah Lucy
Zhang, Shiyi
Lin, Jiaqi
Langer, Robert
Traverso, Giovanni
Date Issued
2016
Journal
Advanced Healthcare Materials
Publisher
Wiley
Citation
Lee, Y. L., et al. "A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention." Adv Healthc Mater (2016).
Version
Author's final manuscript
Abstract
A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1002/ADHM.201501036