Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence
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Saeij_Communication between.pdf
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410.38 KB
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Adobe PDF
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Author(s)
Blader, Ira J.
Saeij, Jeroen
Date Issued
April 2009
Journal
Apmis
Publisher
Wiley Blackwell
Citation
Blader, Ira J., and Jeroen P. Saeij. “Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence.” APMIS 117.5-6 (2009): 458–476.
Version
Author's final manuscript
Abstract
Toxoplasma gondii is an obligate intracellular protozoan parasite that can infect most warm-blooded animals and cause severe and life-threatening disease in developing fetuses and in immune-compromised patients. Although Toxoplasma was discovered over 100 years ago, we are only now beginning to appreciate the importance of the role that parasite modulation of its host has on parasite growth, bradyzoite development, immune evasion, and virulence. The goal of this review is to highlight these findings, to develop an integrated model for communication between Toxoplasma and its host, and to discuss new questions that arise out of these studies.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1111/j.1600-0463.2009.02453.x
