Protein knot server: detection of knots in protein structures
Name
Kolesov-2007-Protein knot server.pdf
Size
1.65 MB
Format
Adobe PDF
Checksum (MD5)
b0a05d3a200f4b3484dd534599520da6
Author(s)
Kolesov, Grigory
Virnau, Peter
Kardar, Mehran
Mirny, Leonid A.
Date Issued
May 2007
Journal
Nucleic Acids Research
Publisher
Oxford University Press
Citation
Kolesov, G. et al. “Protein Knot Server: Detection of Knots in Protein Structures.” Nucleic Acids Research 35.Web Server (2007): W425–W428. Web.
Version
Final published version
Abstract
KNOTS (http://knots.mit.edu) is a web server that detects knots in protein structures. Several protein structures have been reported to contain intricate knots. The physiological role of knots and their effect on folding and evolution is an area of active research. The user submits a PDB id or uploads a 3D protein structure in PDB or mmCIF format. The current implementation of the server uses the Alexander polynomial to detect knots. The results of the analysis that are presented to the user are the location of the knot in the structure, the type of the knot and an interactive visualization of the knot. The results can also be downloaded and viewed offline. The server also maintains a regularly updated list of known knots in protein structures.
MIT Department
Whitaker College of Health Sciences and Technology
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Physics
Terms of Use
Creative Commons Attribution Non-Commercial
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1093/nar/gkm312
