Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin
Name
nihms-1599420.pdf
Description
Accepted version
Size
2.07 MB
Format
Adobe PDF
Checksum (MD5)
7b0ea302c5f80c13d0b1b66a1a4a834b
Author(s)
LeRoux, Michele
Culviner, Peter H
Liu, Yue J
Littlehale, Megan L
Laub, Michael T
Date Issued
2020
Journal
Molecular Cell
Publisher
Elsevier BV
Version
Author's final manuscript
Abstract
© 2020 Elsevier Inc. The toxin-antitoxin (TA) systems encoded on bacterial chromosomes have long been thought to act as effectors of a cellular stress response system. LeRoux et al. find that, despite strong transcriptional induction following various stress treatments, the toxins of TA systems are not activated under these conditions.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Howard Hughes Medical Institute
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.MOLCEL.2020.05.028
