Optoelectronic holographic otoscope for measurement of nano-displacements in tympanic membranes
Name
Hernandez-Montes-2009-Optoelectronic holog.pdf
Size
1.09 MB
Format
Adobe PDF
Checksum (MD5)
e0c1724a106a1bfa2d433f9cf2b49602
Author(s)
Rosowski, John J.
Furlong, Cosme
Santoyo, Fernando Mendoza
Ravicz, Michael E.
Cheng, Jeffrey Tao
Harrington, Ellery
Hulli, Nesim
Hernández-Montes, Maria del Socorro
Santoyo, Fernando Mendoza
Date Issued
June 2009
Journal
Journal of Biomedical Optics
Publisher
Society of Photo-Optical Instrumentation Engineers
Citation
Hernandez-Montes, Maria del Socorro et al. “Optoelectronic holographic otoscope for measurement of nano-displacements in tympanic membranes.” Journal of Biomedical Optics 14.3 (2009): 034023-9. © 2009 Society of Photo-Optical Instrumentation Engineers
Version
Final published version
Abstract
Current methodologies for characterizing tympanic membrane (TM) motion are usually limited to either average acoustic estimates (admittance or reflectance) or single-point mobility measurements, neither of which suffices to characterize the detailed mechanical response of the TM to sound. Furthermore, while acoustic and single-point measurements may aid in diagnosing some middle-ear disorders, they are not always useful. Measurements of the motion of the entire TM surface can provide more information than these other techniques and may be superior for diagnosing pathology. We present advances in our development of a new compact optoelectronic holographic otoscope (OEHO) system for full field-of-view characterization of nanometer-scale sound-induced displacements of the TM surface at video rates. The OEHO system consists of a fiber optic subsystem, a compact otoscope head, and a high-speed image processing computer with advanced software for recording and processing holographic images coupled to a computer-controlled sound-stimulation and recording system. A prototype OEHO system is in use in a medical research environment to address basic science questions regarding TM function. The prototype provides real-time observation of sound-induced TM displacement patterns over a broad frequency range. Representative time-averaged and stroboscopic holographic interferometry results in animals and human cadaver samples are shown, and their potential utility is discussed.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Research Laboratory of Electronics
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
http://dx.doi.org/10.1117/1.3153898
