RNA-Mediated Feedback Control of Transcriptional Condensates
Name
nihms-1649382.pdf
Description
Accepted version
Size
2.86 MB
Format
Adobe PDF
Checksum (MD5)
b1e3167afc784545e951ba957229fa7c
Author(s) • • • • • • • • •
Henninger, Jonathan E
Oksuz, Ozgur
Shrinivas, Krishna
Sagi, Ido
LeRoy, Gary
Zheng, Ming M
Andrews, J Owen
Zamudio, Alicia V
Lazaris, Charalampos
Hannett, Nancy M
Date Issued
2021
Journal
Cell
Publisher
Elsevier BV
Citation
Henninger, Jonathan E, Oksuz, Ozgur, Shrinivas, Krishna, Sagi, Ido, LeRoy, Gary et al. 2021. "RNA-Mediated Feedback Control of Transcriptional Condensates." Cell, 184 (1).
Version
Author's final manuscript
Abstract
© 2020 Elsevier Inc. During the early steps of transcription initiation, nascent RNAs stimulate transcriptional condensate formation, whereas the burst of RNAs produced during elongation stimulates condensate dissolution.
MIT Department
Whitehead Institute for Biomedical Research
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Biology
Massachusetts Institute of Technology. Department of Physics
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Koch Institute for Integrative Cancer Research at MIT
Ragon Institute of MGH, MIT and Harvard
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.CELL.2020.11.030