Synthesis of Solid 2-Pyridylzinc Reagents and Their Application in Negishi Reactions
Name
Buchwald_Synthesis of.pdf
Size
712.98 KB
Format
Adobe PDF
Checksum (MD5)
478f469bf2cf3006a743a0117114f8c5
Author(s)
Bernhardt, Sebastian
Stathakis, Christos
Knochel, Paul
Colombe, James Robert
Buchwald, Stephen Leffler
Date Issued
November 2013
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Colombe, James R., Sebastian Bernhardt, Christos Stathakis, Stephen L. Buchwald, and Paul Knochel. “Synthesis of Solid 2-Pyridylzinc Reagents and Their Application in Negishi Reactions.” Org. Lett. 15, no. 22 (November 15, 2013): 5754–5757.
Version
Author's final manuscript
Abstract
In search of alternatives to unstable or unreliable 2-pyridylboron reagents, we have explored two new varieties of solid, moderately air-stable 2-pyridylzinc reagents. Both reagents can be manipulated in air and are competent nucleophiles in Negishi cross-coupling reactions.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1021/ol402798z
