Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries
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nihms-454564.pdf
Description
Accepted version
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890.96 KB
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Adobe PDF
Checksum (MD5)
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Author(s)
Tekin, Halil
Sanchez, Jefferson G
Landeros, Christian
Dubbin, Karen
Langer, Robert
Khademhosseini, Ali
Date Issued
2012
Journal
Advanced Materials
Publisher
Wiley
Citation
Tekin, H., et al. "Controlling Spatial Organization of Multiple Cell Types in Defined 3d Geometries." Adv Mater (2012).
Version
Author's final manuscript
Abstract
A simple method to control spatial organizations of multiple cell types in predefined geometries by using poly(N-isopropylacrylamide)-based dynamic microwells is described. Dynamic microwells are used to pattern two different cell types in a spatially controlled manner by exploiting their shape changing properties at two different temperatures. Both spatial organization of two different cell types and control of pattern geometry are achieved with circular and square dynamic microwells. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Koch Institute for Integrative Cancer Research at MIT
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
10.1002/adma.201201805
