Single cell biology—a Keystone Symposia report
Name
2021_KeystoneSingleCell.pdf
Description
Accepted version
Size
4.16 MB
Format
Unknown
Checksum (MD5)
8ea2e624a933ed73b867e3fb3821a4ed
Author(s)
Galloway, Kate E
Date Issued
2021
Journal
Annals of the New York Academy of Sciences
Publisher
Wiley
Citation
2021. "Single cell biology—a Keystone Symposia report." Annals of the New York Academy of Sciences, 1506 (1).
Version
Author's final manuscript
Abstract
Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer picture of the variation among and between different cell types. New techniques are beginning to unravel how differences in cell state-transcriptional, epigenetic, and other characteristics-can lead to different cell fates among genetically identical cells, which underlies complex processes such as embryonic development, drug resistance, response to injury, and cellular reprogramming. Single cell technologies also pose significant challenges relating to processing and analyzing vast amounts of data collected. To realize the potential of single cell technologies, new computational approaches are needed. On March 17-19, 2021, experts in single cell biology met virtually for the Keystone eSymposium "Single Cell Biology" to discuss advances both in single cell applications and technologies.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1111/NYAS.14692
